Eurycoma longifolia jack 'Tongkat Ali' has been used to improve male virility and sexual prowess as part of ongoing cultural tradition.

New research demonstrates a scientific basis for its historical use due to the plant’s androgenic effects.
The androgen-boosting effects of this plant include enhanced libido and sexual activity in laboratory animals.
[20-22] Anecdotal reports have also shown a beneficial increase in male testosterone levels as well.
Because of these findings, Eurycoma longifolia has become a popular addition to male health regimens. Myricetin is a flavonoid also found in Euycoma longifolia. Myricetin works to inhibit the enzyme 5 alpha reductase, thereby preventing the conversion of testosterone to the prostate-damaging 5 hydroxytestosterone. [23-24] Myricetin is thought to have greater bioavailability than other flavonoids, making it an excellent addition to a hormone targeted prevention program.

Re-establishing testosterone levels can prove to be highly beneficial for men suffering the effects of lowered hormone levels.
Incorporating a supplement that uses the above-mentioned nutrients into a regimen for men at risk for hormone imbalance is a practical way to address this issue.

Providing these nutrients before hormone imbalance becomes completely symptomatic will afford the patient a much lower risk of suffering from low-testosterone-associated conditions. Raising testosterone levels can lead to a reversal of symptoms such as fatigue, low libido, diminished drive and motivation as well as several physical conditions including reversal of adiposity, gains in strength, improved cognitive function, improved bone health and possibly heart disease prevention.[25]

Tongkat ali Eurycoma longifolia Jack commonly has been successfully used in southeast Asia for generations to increase male virility and sexual prowess. The roots are the most valuable component and are used for the treatment of aches, persistent fever, malaria, sexual insufficiency, dysentery, glandular swelling, and as health supplements. Root extract of the plant have been administered for restoring energy and vitality, enhancing blood flow and functioning as a herbal ingredient for women after child birth.

    

Plaplai Plueak aka: 'Tongkat ali' (Eurycoma longifolia jack)
Flavonols: Quercetin, Myricetin and Kaempferol.
Canthin-6-one alkaloids, -ß- carboline alkaloids, quassinoids, quassinoid diterpenoids,
Eurycomaoside, tirucallane-type triterpenes, squalene derivatives, biphenylneolignans,
eurycolactone, laurycolactone, and eurycomalactone.

References

Heller CG, Myers GB. The male climacteric: Its symptomatology, diagnosis and treatment. JAMA 1944;126:472.
Basaria S, Dobs AS. Hypogonadism and androgen replacement therapy in elderly men. Am J Med 2001;110(7):563-72.
Gray A, Feldman HA, McKinlay JB. Age, disease, and changing sex hormone levels in middle-aged men: results of the Massachusetts Male Aging Study. J Clin Endocrinol Metab 1991;73(5):1016-25.
Nieschlag E, Behre HM, eds. Testosterone: action, deficiency, substitution. 2nd ed. Berlin: Springer-Verlag, 1998:58-66.
Raynor MC, Carson CC, Pearson MD, Nix JW. Androgen deficiency in the aging male: a guide to diagnosis and testosterone replacement therapy. Can J Urol. 2007 Dec;14 Suppl 1:63-8.
Rosano GM, Sheiban I, Massaro R, Pagnotta P, Marazzi G, Vitale C, Mercuro G, Volterrani M, Aversa A, Fini M. Low testosterone levels are associated with coronary artery disease in male patients
with angina. Int J Impot Res. 2007 Mar-Apr;19(2):176-82. Epub 2006 Aug 31.
Zitzmann M. Therapy of male hypogonadism. Internist (Berl). 2008 May;49(5):559-569.
Sternbach H. Age-associated testosterone decline in men: clinical issues for psychiatry. Am J Psychiatry. 1998 Oct;155(10):1310-8.
Schottner M, Gansser D, Spiteller G, et al. Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG). Planta Med 1997;63:529-32.
Hyrb D et al. The effect of extracts of the roots of the stinging nettle (Urtica dioca) on the interaction of SHBG with its receptor on human prostatic membranes. Planta Med, 1995, 61:31-32.
Konrad L, Muller HH, Lenz C, et al. Antiproliferative effect on human prostate cancer cells by a stinging nettle root (Urtica dioica) extract. Planta Med 2000;66:44-7.
Lichius JJ, Muth C. The inhibiting effects of Urtica dioica root extracts on experimentally induced prostatic hyperplasia in the mouse. Planta Med 1997;63:307-10.
Durak I, Biri H, Devrim E, et al. Aqueous extract of Urtica dioica makes significant inhibition on adenosine deaminase activity in prostate tissue from patients with prostate cancer. Cancer Biol Ther 2004;3:855-7.
Kassen A, Berges R, Senge T, et al. Effect of beta-sitosterol on transforming growth factor-beta-1 expression and translocation protein kinase C alpha in human prostate stromal cells in vitro. Eur Urol 2000;37:735-41.
Berges R, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet. 1995;345:1529-32.
Klippel K, et al. A multicentric placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. German BPH-Phyto Study Group. Br J Urol. 1997; 80:427-32.
Shimoi K, et al. Intestinal absorption of luteolin 7-O-beta-glucoside in rats and humans. FEBS Lett. 1998;438:220-24.
Shimoi K, et al. Metabolic fate of luteolin and its functional activity at focal site. Biofactors. 2000;12:181-6.
Saarinen N et al. No evidence for the in vivo activity of aromatase-inhibiting flavonoids. J Steroid Biochem Mol Biol 2001, 78:231-39.
Ang HH, Cheang HS, Yusof AP. Effects of Eurycoma longifolia Jack (Tongkat Ali) on the initiation of sexual performance of inexperienced castrated male rats. Exp Anim 2000;49:35-8.
Ang HH, Ikeda S, Gan EK. Evaluation of the potency activity of aphrodisiac in Eurycoma longifolia Jack. Phytother Res 2001;15:435-6.
Ang HH, Sim MK. Eurycoma longifolia Jack enhances libido in sexually experienced male rats. Exp Anim 1997;46:287-90.
Matsuda H, et al. Anti-androgenic activity of Myricae cortex-Isolation of active constituents from bark of Myrica rubra. Biol Pharm Bull. 2001; 24:259-63.
Hiipakka RA, Structure-activity relationships for inhibition of human 5alpha-reductases by polyphenols. Biochem Pharmacol. 2002 Mar 15;63(6):1165-76.
Debing E, et al. Men with atherosclerotic stenosis of the carotid artery have lower testosterone levels compared with controls. Int Angiol. 2008 Apr;27(2):135-41.

return to Tongkat ali main page

Intellectual properties contained herein © (p) copyright 2001-2018 worldwide rights reserved
Siam Natural Organics Siam Industries International